Publications of A. Bar-Even

Yishai, O., Lindner, S. N., Gonzalez de la Cruz, J., Tenenboim, H. & Bar-Even, A. The formate bio-economy. Current Opinion in Chemical Biology 35, 1–9 (2016).

Poust, S., Piety, J., Bar-Even, A., Louw, C., Baker, D., Keasling, J. D. & Siegel, J. B. Mechanistic Analysis of an Engineered Enzyme that Catalyzes the Formose Reaction. Chembiochem 16, 1950–1954 (2015).

Siegel, J. B., Smith, A. L., Poust, S., Wargacki, A. J., Bar-Even, A., Louw, C., Shen, B. W., Eiben, C. B., Tran, H. M., Noor, E., Gallaher, J. L., Bale, J., Yoshikuni, Y., Gelb, M. H., Keasling, J. D., Stoddard, B. L., Lidstrom, M. E. & Baker, D. Computational protein design enables a novel one-carbon assimilation pathway. Proceedings of the National Academy of Sciences of the United States of America 112, 3704–3709 (2015).

Bar-Even, A., Milo, R., Noor, E. & Tawfik, D. S. The Moderately Efficient Enzyme: Futile Encounters and Enzyme Floppiness. Biochemistry 54, 4969–4977 (2015).

Zelcbuch, L., Razo-Mejia, M., Herz, E., Yahav, S., Antonovsky, N., Kroytoro, H., Milo, R. & Bar-Even, A. An In Vivo Metabolic Approach for Deciphering the Product Specificity of Glycerate Kinase Proves that Both E. coli's Glycerate Kinases Generate 2-Phosphoglycerate. PLoS One 10, (2015).

Noor, E., Bar-Even, A., Flamholz, A., Reznik, E., Liebermeister, W. & Milo, R. Pathway Thermodynamics Highlights Kinetic Obstacles in Central Metabolism. PLoS Computational Biology 10, (2014).

Jinich, A., Rappoport, D., Dunn, I., Sanchez-Lengeling, B., Olivares-Amaya, R., Noor, E., Bar-Even, A. & Aspuru-Guzik, A. Quantum Chemical Approach to Estimating the Thermodynamics of Metabolic Reactions. Scientific Reports 4, (2014).

Zelcbuch, L., Antonovsky, N., Bar-Even, A., Levin-Karp, A., Barenholz, U., Dayagi, M., Liebermeister, W., Flamholz, A., Noor, E., Amram, S., Brandis, A., Bareia, T., Yofe, I., Jubran, H. & Milo, R. Spanning high-dimensional expression space using ribosome-binding site combinatorics. Nucleic Acids Research 41, (2013).

Bar-Even, A. & Tawfik, D. S. Engineering specialized metabolic pathways-is there a room for enzyme improvements? Current Opinion in Biotechnology 24, 310–319 (2013).

Bar-Even, A. Does acetogenesis really require especially low reduction potential? Biochimica et Biophysica Acta-Bioenergetics 1827, 395–400 (2013).

Bar-Even, A., Noor, E., Flamholz, A. & Milo, R. Design and analysis of metabolic pathways supporting formatotrophic growth for electricity-dependent cultivation of microbes. SI 1827, 1039–1047 (2013).

Flamholz, A., Noor, E., Bar-Even, A., Liebermeister, W. & Milo, R. Glycolytic strategy as a tradeoff between energy yield and protein cost. Proceedings of the National Academy of Sciences of the United States of America 110, 10039–10044 (2013).

Bar-Even, A., Flamholz, A., Noor, E. & Milo, R. Thermodynamic constraints shape the structure of carbon fixation pathways. Biochimica et Biophysica Acta-Bioenergetics 1817, 1646–1659 (2012).

Bar-Even, A., Flamholz, A., Noor, E. & Milo, R. Rethinking glycolysis: on the biochemical logic of metabolic pathways. Nature Chemical Biology 8, 509–517 (2012).

Flamholz, A., Noor, E., Bar-Even, A. & Milo, R. eQuilibrator-the biochemical thermodynamics calculator. Nucleic Acids Research 40, D770–D775 (2012).

Noor, E., Bar-Even, A., Flamholz, A., Lubling, Y., Davidi, D. & Milo, R. An integrated open framework for thermodynamics of reactions that combines accuracy and coverage. Bioinformatics 28, 2037–2044 (2012).

Bar-Even, A., Noor, E., Flamholz, A., Buescher, J. M. & Milo, R. Hydrophobicity and Charge Shape Cellular Metabolite Concentrations. PLoS Computational Biology 7, (2011).

Bar-Even, A., Noor, E., Savir, Y., Liebermeister, W., Davidi, D., Tawfik, D. S. & Milo, R. The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters. Biochemistry 50, 4402–4410 (2011).

Bar-Even, A., Noor, E., Lewis, N. E. & Milo, R. Design and analysis of synthetic carbon fixation pathways. Proceedings of the National Academy of Sciences of the United States of America 107, 8889–8894 (2010).

Bar-Even, A., Paulsson, J., Maheshri, N., Carmi, M., O'Shea, E., Pilpel, Y. & Barkai, N. Noise in protein expression scales with natural protein abundance. Nature Genetics 38, 636–643 (2006).