Publications of A. Bar-Even

Erb, T. J.; Jones, P. R.; Bar-Even, A.: Synthetic metabolism: metabolic engineering meets enzyme design. Current Opinion in Chemical Biology 37, pp. 56 - 62 (2017)

Yishai, O.; Goldbach, L.; Tenenboim, H.; Lindner, S. N.; Bar-Even, A.: Engineered Assimilation of Exogenous and Endogenous Formate in Escherichia coli. ACS Synthetic Biology 6 (9), pp. 1722 - 1731 (2017)

Bar-Even, A.: Formate Assimilation: The Metabolic Architecture of Natural and Synthetic Pathways. Biochemistry 55 (28), pp. 3851 - 3863 (2016)

Zelcbuch, L.; Lindner, S. N.; Zegman, Y.; Slutskin, I. V.; Antonovsky, N.; Gleizer, S.; Milo, R.; Bar-Even, A.: Pyruvate Formate-Lyase Enables Efficient Growth of Escherichia coli on Acetate and Formate. Biochemistry 55 (17), pp. 2423 - 2426 (2016)

Davidia, D.; Noorb, E.; Liebermeisterc, W.; Bar-Even, A.; Flamholze, A.; Tummlerf, K.; Barenholza, U.; Goldenfelda, M.; Shlomig, T.; Miloa, R.: Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitro k cat measurements. Proceedings of the National Academy of Sciences of the United States of America 113 (12), pp. 3401 - 3406 (2016)

Noor, E.; Flamholz, A.; Bar-Even, A.; Davidi, D.; Milo, R.; Liebermeister, W.: The Protein Cost of Metabolic Fluxes: Prediction from Enzymatic Rate Laws and Cost Minimization. PLoS Computational Biology 12 (11), e1005167 (2016)

Yishai, O.; Lindner, S. N.; Gonzalez de la Cruz, J.; Tenenboim, H.; Bar-Even, A.: The formate bio-economy. Current Opinion in Chemical Biology 35, pp. 1 - 9 (2016)

Poust, S.; Piety, J.; Bar-Even, A.; Louw, C.; Baker, D.; Keasling, J. D.; Siegel, J. B.: Mechanistic Analysis of an Engineered Enzyme that Catalyzes the Formose Reaction. Chembiochem 16 (13), pp. 1950 - 1954 (2015)

Siegel, J. B.; Smith, A. L.; Poust, S.; Wargacki, A. J.; Bar-Even, A.; Louw, C.; Shen, B. W.; Eiben, C. B.; Tran, H. M.; Noor, E. et al.; Gallaher, J. L.; Bale, J.; Yoshikuni, Y.; Gelb, M. H.; Keasling, J. D.; Stoddard, B. L.; Lidstrom, M. E.; Baker, D.: Computational protein design enables a novel one-carbon assimilation pathway. Proceedings of the National Academy of Sciences of the United States of America 112 (12), pp. 3704 - 3709 (2015)

Bar-Even, A.; Milo, R.; Noor, E.; Tawfik, D. S.: The Moderately Efficient Enzyme: Futile Encounters and Enzyme Floppiness. Biochemistry 54 (32), pp. 4969 - 4977 (2015)

Zelcbuch, L.; Razo-Mejia, M.; Herz, E.; Yahav, S.; Antonovsky, N.; Kroytoro, H.; Milo, R.; Bar-Even, A.: An In Vivo Metabolic Approach for Deciphering the Product Specificity of Glycerate Kinase Proves that Both E. coli's Glycerate Kinases Generate 2-Phosphoglycerate. PLoS One 10 (3), e0122957 (2015)

Noor, E.; Bar-Even, A.; Flamholz, A.; Reznik, E.; Liebermeister, W.; Milo, R.: Pathway Thermodynamics Highlights Kinetic Obstacles in Central Metabolism. PLoS Computational Biology 10 (2), e1003483 (2014)

Jinich, A.; Rappoport, D.; Dunn, I.; Sanchez-Lengeling, B.; Olivares-Amaya, R.; Noor, E.; Bar-Even, A.; Aspuru-Guzik, A.: Quantum Chemical Approach to Estimating the Thermodynamics of Metabolic Reactions. Scientific Reports 4, 7022 (2014)

Zelcbuch, L.; Antonovsky, N.; Bar-Even, A.; Levin-Karp, A.; Barenholz, U.; Dayagi, M.; Liebermeister, W.; Flamholz, A.; Noor, E.; Amram, S. et al.; Brandis, A.; Bareia, T.; Yofe, I.; Jubran, H.; Milo, R.: Spanning high-dimensional expression space using ribosome-binding site combinatorics. Nucleic Acids Research 41 (9), e98 (2013)

Bar-Even, A.; Tawfik, D. S.: Engineering specialized metabolic pathways-is there a room for enzyme improvements? Current Opinion in Biotechnology 24 (2), pp. 310 - 319 (2013)

Bar-Even, A.: Does acetogenesis really require especially low reduction potential? Biochimica et Biophysica Acta-Bioenergetics 1827 (3), pp. 395 - 400 (2013)

Bar-Even, A.; Noor, E.; Flamholz, A.; Milo, R.: Design and analysis of metabolic pathways supporting formatotrophic growth for electricity-dependent cultivation of microbes. SI 1827 (8-9), pp. 1039 - 1047 (2013)

Flamholz, A.; Noor, E.; Bar-Even, A.; Liebermeister, W.; Milo, R.: Glycolytic strategy as a tradeoff between energy yield and protein cost. Proceedings of the National Academy of Sciences of the United States of America 110 (24), pp. 10039 - 10044 (2013)

Noor, E.; Flamholz, A.; Liebermeister, W.; Bar-Even, A.; Milo, R.: A note on the kinetics of enzyme action: A decomposition that highlights thermodynamic effects. SI 587 (17), pp. 2772 - 2777 (2013)

Bar-Even, A.; Flamholz, A.; Noor, E.; Milo, R.: Thermodynamic constraints shape the structure of carbon fixation pathways. Biochimica et Biophysica Acta-Bioenergetics 1817 (9), pp. 1646 - 1659 (2012)