Publications of Arren Bar-Even

Wenk, S.; Rainaldi, V.; Schann, K.; He, H.; Bouzon, M.; Döring, V.; Lindner, S. N.; Bar-Even, A.: Evolution-assisted engineering of E. coli enables growth on formic acid at ambient CO2 via the Serine Threonine Cycle. Metabolic Engineering 88, pp. 14 - 24 (2025)

Wenk, S.; Rainaldi, V.; Schann, K.; He, H.; Bouzon, M.; Döring, V.; Lindner, S. N.; Bar-Even, A.: Evolution-assisted engineering of E. coli enables growth on formic acid at ambient CO2 via the Serine Threonine Cycle. Metabolic Engineering 88, pp. 14 - 24 (2025)

Schann, K.; Bakker, J.; Boinot, M.; Kuschel, P.; He, H.; Nattermann, M.; Paczia, N.; Erb, T.; Bar-Even, A.; Wenk, S.: Design, construction and optimization of formaldehyde growth biosensors with broad application in biotechnology. Microbial Biotechnology 17 (7), e14527 (2024)

Schulz-Mirbach, H. A. M.; Kruesemann, J. L.; Andreadaki, T.; Nerlich, J. N.; Mavrothalassiti, E.; Boecker, S.; Schneider, P.; Weresow, M.; Abdelwahab, O.; Paczia, N. et al.; Dronsella, B.; Erb, T. J.; Bar-Even, A.; Klamt, S.; Lindner, S. N.: Engineering new-to-nature biochemical conversions by combining fermentative metabolism with respiratory modules. Nature Communications 15 (1), 6725 (2024)

Bysani, V. R.; Alam, A. S.M.; Bar-Even, A.; Machens, F.: Engineering and evolution of the complete Reductive Glycine Pathway in Saccharomyces cerevisiae for formate and CO2 assimilation. Metabolic Engineering 81, pp. 167 - 181 (2023)

Schada von Borzyskowski, L.; Schulz-Mirbach, H.; Troncoso Castellanos, M.; Severi, F.; Gomez Coronado, P. A.; Paczia, N.; Glatter, T.; Bar-Even, A.; Lindner, S. N.; Erb, T.J.: Implementation of the β-hydroxyaspartate cycle increases growth performance of Pseudomonas putida on the PET monomer ethylene glycol. Metabolic Engineering 76, pp. 97 - 109 (2023)

Kim, S.; Giraldo, N.; Rainaldi, V.; Machens, F.; Collas, F.; Kubis, A.; Kensy, F.; Bar-Even, A.; Lindner, S. N.: Optimizing E. coli as a formatotrophic platform for bioproduction via the reductive glycine pathway. Frontiers in Bioengineering and Biotechnology 11, 1091899 (2023)

Wu, T.; Gomez Coronado, P. A.; Kubis, A.; Lindner, S. N.; Marlière, P.; Erb, T.J.; Bar-Even, A.; He, H.: Engineering a synthetic energy-efficient formaldehyde assimilation cycle in Escherichia coli. Nature Communications 14, 8490 (2023)

Schulz-Mirbach, H.; Mueller, A.; Wu, T.; Pfister, P.; Aslan, S.; Schada von Borzyskowski, L.; Erb , T.J.; Bar-Even, A.; Lindner, S. N.: On the flexibility of the cellular amination network in E. coli. eLife 11, e77492 (2022)

Iacometti, C.; Marx, K.; Hönick, M.; Biletskaia, V.; Schulz-Mirbach, H.; Dronsella, B.; Satanowski, A.; Delmas, V.A.; Berger, A.; Dubois, I. et al.; Bouzon, M.; Döring, V.; Noor, E.; Bar-Even, A.; Lindner, S. N.: Activating Silent Glycolysis Bypasses in Escherichia coli. BioDesign Research 2022, 9859643 (2022)

Kirst, H.; Ferlez, B.H.; Lindner, S. N.; Cotton, C. A. R.; Bar-Even, A.; Kerfeld, C.A.: Toward a glycyl radical enzyme containing synthetic bacterial microcompartment to produce pyruvate from formate and acetate. Proceedings of the National Academy of Sciences of the United States of America 119 (8), e2116871119 (2022)

Bouzon, M.; Döring, V.; Dubois, I.; Berger, A.; Stoffel, G.M.M.; Ramirez, L. C.; Meyer, S.N.; Fouré, M.; Roche, D.; Perret, A. et al.; Erb, T.J.; Bar-Even, A.; Lindner, S. N.: Change in cofactor specificity of oxidoreductases by adaptive evolution of an escherichia coli nadph-auxotrophic strain. mBio 12 (4), e00329-21 (2021)

Leger, D.; Matassa, S.; Noor, E.; Shepon, A.; Milo, R.; Bar-Even, A.: Photovoltaic-driven microbial protein production can use land and sunlight more efficiently than conventional crops. Proceedings of the National Academy of Sciences of the United States of America 118 (26), e2015025118 (2021)

Scheffen, M.; Marchal, D.G.; Beneyton, T.; Schuller, S.K.; Klose, M.; Diehl, C.; Lehmann, J.; Pfister, P.; Carrillo, M.; He, H. et al.; Aslan, S.; Cortina, N.S.; Claus, P.; Bollschweiler, D.; Baret, J.-C.; Schuller, J.M.; Zarzycki, J.; Bar-Even, A.; Erb, T.J.: A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation. Nature Catalysis 4, pp. 105 - 115 (2021)

Cotton, C. A. R.; Bernhardsgrütter, I.; He, H.; Burgener, S.; Schulz, L.; Paczia, N.; Dronsella, B.; Erban, A.; Toman, S.; Dempfle, M. et al.; de Maria, A.; Kopka, J.; Lindner, S. N.; Erb, T. J.; Bar-Even, A.: Underground isoleucine biosynthesis pathways in E. coli. eLife 9, e54207 (2020)

Ramirez, L. C.; Calvo Tusell, C.; Stoffel, G. M. M.; Lindner, S. N.; Osuna, S.; Erb, T. J.; Garcia-Borràs, M.; Bar-Even, A.; Acevedo-Rocha, C. G.: In vivo selection for formate dehydrogenases with high efficiency and specificity towards NADP+. ACS Catalysis 10, pp. 7512 - 7525 (2020)

Aslan, S.; Noor, E.; Benito-Vaquerizo, S.; Lindner, S. N.; Bar-Even, A.: Design and engineering of E. coli metabolic sensor strains with a wide sensitivity range for glycerate. Metabolic Engineering 57, pp. 96 - 109 (2020)

Claassens, N. J.; Bordanaba-Florit, G.; Cotton, C. A. R.; de Maria, A.; Finger-Bou, M.; Friedeheim, L.; Giner-Laguarda, N.; Munar-Palmer, M.; Newell, W.; Scarinci, G. et al.; Verbunt, J.; de Vries, S.T.; Yilmaz, S.; Bar-Even, A.: Replacing the Calvin cycle with the reductive glycine pathway in Cupriavidus necator. Metabolic Engineering 62, pp. 30 - 41 (2020)

Claassens, N. J.; Scarinci, G.; Fischer, A.; Flamholz, A.I.; Newell, W.; Frielingsdorf, S.; Lenz, O.; Bar-Even, A.: Phosphoglycolate salvage in a chemolithoautotroph using the Calvin cycle. Proceedings of the National Academy of Sciences of the United States of America 117 (36), pp. 22452 - 22461 (2020)

Cotton, C. A. R.; Claassens, N. J.; Benito-Vaquerizo, S.; Bar-Even, A.: Renewable methanol and formate as microbial feedstocks. Current Opinion in Biotechnology 62, pp. 168 - 180 (2020)

Flamholz, A.I.; Dugan, E.; Blikstad, C.; Gleizer, S.; Ben-Nissan, R.; Amram, S.; Antonovsky, N.; Ravishankar, S.; Noor, E.; Bar-Even, A. et al.; Milo, R.; Savage, D.F.: Functional reconstitution of a bacterial co2 concentrating mechanism in E. coli. eLife 9, e59882, pp. 1 - 57 (2020)

He, H.; Höper, R.; Dodenhöft, M.; Marlière, P.; Bar-Even, A.: An optimized methanol assimilation pathway relying on promiscuous formaldehyde-condensing aldolases in E. coli. Metabolic Engineering 60, pp. 1 - 13 (2020)

He, H.; Noor, E.; Ramos-Parra, P. A.; García-Valencia, L. E.; Patterson, J. A.; Díaz de la Garza, R. I.; Hanson, A. D.; Bar-Even, A.: In Vivo Rate of Formaldehyde Condensation with Tetrahydrofolate. Metabolites 10 (2), 65 (2020)

Kim, S.; Lindner, S. N.; Aslan, S.; Yishai, O.; Wenk, S.; Schann, K.; Bar-Even, A.: Growth of E. coli on formate and methanol via the reductive glycine pathway. Nature Chemical Biology 16 (5), pp. 538 - 545 (2020)

Lindner, S. N.; Aslan, S.; Mueller, A.; Hoffart, E.; Behrens, P.; Edlich-Muth, C.; Blombach, B.; Bar-Even, A.: A synthetic glycerol assimilation pathway demonstrates biochemical constraints of cellular metabolism. The FEBS Journal 287 (1), pp. 160 - 172 (2020)

Patterson, J.A.; He, H.; Folz, J.S.; Li, Q.; Wilson, M.A.; Fiehn, O.; Bruner, S.D.; Bar-Even, A.; Hanson, A.D.: Thioproline formation as a driver of formaldehyde toxicity in Escherichia coli. Biochemical Journal 477 (9), pp. 1745 - 1757 (2020)

Sánchez-Andrea, I.; Guedes, I.A.; Hornung, B.; Boeren, S.; Lawson, C.E.; Sousa, D.Z.; Bar-Even, A.; Claassens, N. J.; Stams, A.J.M.: The reductive glycine pathway allows autotrophic growth of Desulfovibrio desulfuricans. Nature Communications 11 (1), 5090 (2020)

Satanowski, A.; Bar-Even, A.: A one-carbon path for fixing CO2. EMBO reports 21 (4), e50273 (2020)

Satanowski, A.; Dronsella, B.; Noor, E.; Vögeli, B.; He, H.; Wichmann, P.; Erb, T.J.; Lindner, S. N.; Bar-Even, A.: Awakening a latent carbon fixation cycle in Escherichia coli. Nature Communications 11 (1), 5812 (2020)

Wenk, S.; Schann, K.; He, H.; Rainaldi, V.; Kim, S.; Lindner, S. N.; Bar-Even, A.: An “energy-auxotroph” E. coli provides an in vivo platform for assessing NADH regeneration systems. Biotechnology and Bioengineering 117 (11), pp. 3422 - 3434 (2020)