Max Planck Institute of Molecular Plant Physiology

Publications of Lothar Willmitzer

Journal Article (351)

1.

Journal Article

Schlossarek, D.; Luzarowski, M.; Sokolowska, E.; Gorka, M.; Willmitzer, L.; Skirycz, A.: PROMISed: A novel web-based tool to facilitate analysis and visualization of the molecular interaction networks from co-fractionation mass spectrometry (CF-MS) experiments. Computational and Structural Biotechnology Journal 19, pp. 5117 - 5125 (2021)

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2.

Journal Article

Luzarowski, M.; Vicente, R.; Kiselev, A.; Wagner, M.; Schlossarek, D.; Erban, A.; de Souza, L. P.; Childs, D.; Wojciechowska, I.; Luzarowska, U. et al.; Gorka, M.; Sokolowska, E.; Kosmacz, M.; Moreno, J.C.; Brzezinska, A.; Vegesna, B.; Kopka, J.; Fernie, A. R.; Willmitzer, L.; Ewald, J. C.; Skirycz, A.: Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity. Communications Biology 4 (1), 181 (2021)

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3.

Journal Article

Martín-Pizarro, C.; Vallarino, J. G.; Osorio, S.; Meco, V.; Urrutia, M.; Pillet, J.; Casañal, A.; Merchante, C.; Amaya, I.; Willmitzer, L. et al.; Fernie, A. R.; Giovannoni, J. J.; Botella, M. A.; Valpuesta, V.; Posé, D.: The NAC transcription factor FaRIF controls fruit ripening in strawberry. The Plant Cell 33 (5), pp. 1574 - 1593 (2021)

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4.

Journal Article

Cuadros-Inostroza, Á.; Verdugo-Alegría, C.; Willmitzer, L.; Moreno-Simunovic, Y.; Vallarino, J. G.: Non-Targeted Metabolite Profiles and Sensory Properties Elucidate Commonalities and Differences of Wines Made with the Same Variety but Different Cultivar Clones. Metabolites 10 (6), E220 (2020)

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5.

Journal Article

Pott, D. M.; de Abreu e Lima, F.; Soria, C.; Willmitzer, L.; Fernie, A. R.; Nikoloski, Z.; Osorio, S.; Vallarino, J. G.: Metabolic reconfiguration of strawberry physiology in response to postharvest practices. Food Chemistry 321, 126747 (2020)

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6.

Journal Article

Pott, D. M.; Vallarino, J. G.; Cruz-Rus, E.; Willmitzer, L.; Sanchez-Sevilla, J. F.; Amaya, I.; Osorio, S.: Genetic analysis of phenylpropanoids and antioxidant capacity in strawberry fruit reveals mQTL hotspots and candidate genes. Scientific Reports 10 (1), 20197 (2020)

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7.

Journal Article

Vallarino, J.G.; Merchante, C.; Sánchez-Sevilla, J.F.; de Luis Balaguer, M.A.; Pott, D.M.; Ariza, M.T.; Casañal, A.; Posé, D.; Vioque, A.; Amaya, I. et al.; Willmitzer, L.; Solano, R.; Sozzani, R.; Fernie, A. R.; Botella, M.A.; Giovannoni, J.J.; Valpuesta, V.; Osorio, S.: Characterizing the involvement of FaMADS9 in the regulation of strawberry fruit receptacle development. Plant Biotechnology Journal 18 (4), pp. 929 - 943 (2020)

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8.

Journal Article

Yu, Q.; He, Z.; Zubkov, D.; Huang, S.; Kurochkin, I.; Yang, X.; Halene, T.; Willmitzer, L.; Giavalisco, P.; Akbarian, S. et al.; Khaitovich, P.: Lipidome alterations in human prefrontal cortex during development, aging, and cognitive disorders. Molecular Psychiatry 25 (11), pp. 2952 - 2969 (2020)

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9.

Journal Article

Al-Aama, J.; Al Mahdi, H. B.; Salama, M. A.; Bakur, K.; Alhozali, A.; Mosli, H.; Bahijri, S. M.; Bahieldin, A.; Elango, R.; Willmitzer, L. et al.; Edris, S.: Rapid detection of type II diabetes mellitus in Saudi patients via simultaneous screening of multiple SNPs. Biotechnology & Biotechnology Equipment 33 (1), pp. 1319 - 1326 (2019)

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10.

Journal Article

Al-Aama, J.Y.; Mahdi, H.B.A.; Salama, M.A.; Bakur, K.H.; Alhozali, A.; Mosli, H.H.; Bahijri, S.M.; Bahieldin, A.; Willmitzer, L.; Edris, S.: Detection of secondary metabolites as biomarkers for the early diagnosis and prevention of type 2 diabetes. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 12, pp. 2675 - 2684 (2019)

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11.

Journal Article

Bozek, K.; Khrameeva, E. E.; Reznick, J.; Omerbašić, D.; Bennett, N. C.; Lewin, G. R.; Azpurua, J.; Gorbunova, V.; Seluanov, A.; Regnard, P. et al.; Wanert, F.; Marchal, J.; Pifferi, F.; Aujard, F.; Liu, Z.; Shi, P.; Pääbo, S.; Schröder, F.; Willmitzer, L.; Giavalisco, P.; Khaitovich, P.: Publisher Correction: Lipidome determinants of maximal lifespan in mammals. Scientific Reports 9 (1), 6972 (2019)

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12.

Journal Article

Goehring, I.; Sauter, N. S.; Catchpole, G.; Assmann, A.; Shu, L.; Zien, K. S.; Moehlig, M.; Pfeiffer, A. F. H.; Oberholzer, J.; Willmitzer, L. et al.; Spranger, J.; Maedler, K.: Correction to: Identification of an intracellular metabolic signature impairing beta cell function in the rat beta cell line INS-1E and human islets. Diabetologia 62 (3), pp. 553 - 554 (2019)

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13.

Journal Article

Goehring, I.; Sauter, N. S.; Catchpole, G.; Assmann, A.; Shu, L.; Zien, K. S.; Moehlig, M.; Pfeiffer, A. F. H.; Oberholzer, J.; Willmitzer, L. et al.; Spranger, J.; Maedler, K.: Identification of an intracellular metabolic signature impairing beta cell function in the rat beta cell line INS-1E and human islets (vol 54, pg 2584, 2011). Diabetologia 62 (3), pp. 553 - 554 (2019)

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14.

Journal Article

Kurochkin, I.; Khrameeva, E.; Tkachev, A.; Stepanova, V.; Vanyushkina, A.; Stekolshchikova, E.; Li, Q.; Zubkov, D.; Shichkova, P.; Halene, T. et al.; Willmitzer, L.; Giavalisco, P.; Akbarian, S.; Khaitovich, P.: Metabolome signature of autism in the human prefrontal cortex. Communications Biology 2 (1), 234 (2019)

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15.

Journal Article

Zhang, Q.; Wu, S.; Li, Y.; Liu, M.; Ni, K.; Yi, X.; Shi, Y.; Ma, L.; Willmitzer, L.; Ruan, J.: Characterization of three different classes of non-fermented teas using untargeted metabolomics. Food Research International 121, pp. 697 - 704 (2019)

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16.

Journal Article

de Abreu e Lima, F.; Li, K.; Wen, W.; Yan, J.; Nikoloski, Z.; Willmitzer, L.; Brotman, Y.: Unraveling lipid metabolism in maize with time-resolved multi-omics data. The Plant Journal 93 (6), pp. 1102 - 1115 (2018)

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17.

Journal Article

de Abreu e Lima, F.; Willmitzer, L.; Nikoloski, Z.: Classification-driven framework to predict maize hybrid field performance from metabolic profiles of young parental roots. PLoS One 13 (4), e0196038 (2018)

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18.

Journal Article

Vallarino, J. G.; de Abreu e Lima, F.; Soria, C.; Tong, H.; Pott, D. M.; Willmitzer, L.; Fernie, A. R.; Nikoloski, Z.; Osorio, S.: Genetic diversity of strawberry germplasm using metabolomic biomarkers. Scientific Reports 8 (1), 14386 (2018)

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19.

Journal Article

Veyel, D.; Sokolowska, E.; Moreno, J.C.; Kierszniowska, S.; Cichon, J.; Wojciechowska, I.; Luzarowski, M.; Kosmacz, M.; Szlachetko, J.; Gorka, M. et al.; Meret, M.; Graf, A.; Meyer, E. H.; Willmitzer, L.; Skirycz, A.: PROMIS, global analysis of PROtein-metabolite interactions using size separation in Arabidopsis thaliana. The Journal of Biological Chemistry 293 (32), pp. 12440 - 12453 (2018)

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20.

Journal Article

Wen, W.; Jin, M.; Li, K.; Liu, H.; Xiao, Y.; Zhao, M.; Alseekh, S.; Li, W.; de Abreu e Lima, F.; Brotman, Y. et al.; Willmitzer, L.; Fernie, A. R.; Yan, J.: An integrated multi-layered analysis of the metabolic networks of different tissues uncovers key genetic components of primary metabolism in maize. The Plant Journal 93 (6), pp. 1116 - 1128 (2018)

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21.

Journal Article

Wu, S.; Tohge, T.; Cuadros-Inostroza, A. C.; Tong, H.; Tenenboim, H.; Kooke, R.; Méret, M.; Keurentjes, J. B.; Nikoloski, Z.; Fernie, A. R. et al.; Willmitzer, L.; Brotman, Y.: Mapping the Arabidopsis Metabolic Landscape by Untargeted Metabolomics at Different Environmental Conditions. Molecular Plant 11 (1), pp. 118 - 134 (2018)

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22.

Journal Article

Bozek, K.; Khrameeva, E. E.; Reznick, J.; Omerbašić, D.; Bennett, N. C.; Lewin, G. R.; Azpurua, J.; Gorbunova, V.; Seluanov, A.; Regnard, P. et al.; Wanert, F.; Marchal, J.; Pifferi, F.; Aujard, F.; Liu, Z.; Shi, P.; Pääbo, S.; Schröder, F.; Willmitzer, L.; Giavalisco, P.; Khaitovich, P.: Lipidome determinants of maximal lifespan in mammals. Scientific Reports 7, 5 (2017)

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23.

Journal Article

Bucher, R.; Veyel, D.; Willmitzer, L.; Krattinger, S.; Keller, B.; Biglera, L.: Combined GC- and UHPLC-HR-MS Based Metabolomics to Analyze Durable Anti-fungal Resistance Processes in Cereals. Chimia 71 (4), pp. 156 - 159 (2017)

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24.

Journal Article

de Abreu e Lima, F.; Westhues, M.; Cuadros-Inostroza, Á.; Willmitzer, L.; Melchinger, A. E.; Nikoloski, Z.: Metabolic robustness in young roots underpins a predictive model of maize hybrid performance in the field. The Plant Journal 90 (2), pp. 319 - 329 (2017)

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25.

Journal Article

Jin, M.; Zhang, X.; Zhao, M.; Deng, M.; Du, Y.; Zhou, Y.; Wang, S.; Tohge, T.; Fernie, A. R.; Willmitzer, L. et al.; Brotman, Y.; Yan, J.; Weiwei, W.: Integrated genomics-based mapping reveals the genetics underlying maize flavonoid biosynthesis. BMC Plant Biology 17 (1), 17 (2017)

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26.

Journal Article

Li, Q.; Bozek, K.; Xu, C.; Guo, Y.; Sun, J.; Pääbo, S.; Sherwood, C. C.; Hof, P. R.; Ely, J. J.; Li, Y. et al.; Willmitzer, L.; Giavalisco, P.; Khaitovich, P.: Changes in lipidome composition during brain development in humans, chimpanzees, and macaque monkeys. Molecular Biology and Evolution 34 (5), pp. 1155 - 1166 (2017)

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27.

Journal Article

Luzarowski, M.; Kosmacz, M.; Sokolowska, E.; Jasinska, W.; Willmitzer, L.; Veyel, D.; Skirycz, A.: Affinity purification with metabolomic and proteomic analysis unravels diverse roles of nucleoside diphosphate kinases. Journal of Experimental Botany 68 (13), pp. 3487 - 3499 (2017)

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28.

Journal Article

Veyel, D.; Kierszniowska, S.; Kosmacz, M.; Sokolowska, E.; Michaelis, A.; Luzarowski, M.; Szlachetko, J.; Willmitzer, L.; Skirycz, A.: System-wide detection of protein-small molecule complexes suggests extensive metabolite regulation in plants. Scientific Reports 7, 42387 (2017)

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29.

Journal Article

Westhues, M.; Schrag, T. A.; Heuer, C.; Thaller, G.; Utz, H. F.; Schipprack, W.; Thiemann, A.; Seifert, F.; Ehret, A.; Schlereth, A. et al.; Stitt, M.; Nikoloski, Z.; Willmitzer, L.; Schoen, C. C.; Scholten, S.; Melchinger, A. E.: Omics-based hybrid prediction in maize. Theoretical and Applied Genetics 130 (9), pp. 1927 - 1939 (2017)

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30.

Journal Article

Wen, W.; Brotman, Y.; Willmitzer, L.; Yan, J.; Fernie, A. R.: Broadening Our Portfolio in the Genetic Improvement of Maize Chemical Composition. Trends in Genetics 32 (8), pp. 459 - 469 (2016)

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31.

Journal Article

Cuadros-Inostroza, A. C.; Ruiz-Lara, S.; Gonzalez, E.; Eckardt, A.; Willmitzer, L.; Pena-Cortes, H.: GC-MS metabolic profiling of Cabernet Sauvignon and Merlot cultivars during grapevine berry development and network analysis reveals a stage-and cultivar-dependent connectivity of primary metabolites. Metabolomics 12 (2), 39 (2016)

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32.

Journal Article

Machado, M.; Bromke, M. A.; Domingues Júnior, A.P.; Marçal Vieira Vaz, M.G.; Rosa, R.M.; Vinson, C.C.; Sabir, J.S.; Rocha, D.I.; Martins, M.A.; Araújo, W.L. et al.; Willmitzer, L.; Szymanski, J.; Nunes-Nesi, A.: Comprehensive metabolic reprograming in freshwater Nitzschia palea strains undergoing nitrogen starvation is likely associated with its ecological origin. Algal Research 18, pp. 116 - 126 (2016)

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33.

Journal Article

Riewe, D.; Jeon, H.-J.; Lisec, J.; Heuermann, M. C.; Schmeichel, J.; Seyfarth, M.; Meyer, R. C.; Willmitzer, L.; Altmann, T.: A naturally occurring promoter polymorphism of the Arabidopsis FUM2 gene causes expression variation, and is associated with metabolic and growth traits. The Plant Journal 88, pp. 826 - 838 (2016)

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34.

Journal Article

Rudovich, N. N.; Pivovarova, O.; Mazuch, J.; Wendt, S.; Tuvia, N.; Kruse, M.; Nikiforova, V.; Murahovschi, V.; Erban, A.; Mosig, A. et al.; Sticht, C.; Goegebakan, O.; Willmitzer, L.; Kramer, A.; Pfeiffer, A. F.: Insulin directly regulates clock gene expression in the insulin-dependent tissues in vivo and in vitro. Diabetologia 59, p. S324 - S324 (2016)

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35.

Journal Article

Scossa, F.; Brotman, Y.; de Abreu e Lima, F.; Willmitzer, L.; Nikoloski, Z.; Tohge, T.; Fernie, A. R.: Genomics-based strategies for the use of natural variation in the improvement of crop metabolism. Plant Science 242, pp. 47 - 64 (2016)

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36.

Journal Article

Skirycz, A.; Kierszniowska, S.; Meret, M.; Willmitzer, L.; Tzotzos, G.: Medicinal Bioprospecting of the Amazon Rainforest: A Modern Eldorado ? Trends in Biotechnology 34 (10), pp. 781 - 790 (2016)

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37.

Journal Article

Tenenboim, H.; Burgos, A.; Willmitzer, L.; Brotman, Y.: Using lipidomics for expanding the knowledge on lipid metabolism in plants. Biochimie 130, pp. 91 - 96 (2016)

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38.

Journal Article

Wu, S.; Alseekh, S.; Cuadros-Inostroza, A. C.; Fusari, C. M.; Mutwil, M.; Kooke, R.; Keurentjes, J. B.; Fernie, A. R.; Willmitzer, L.; Brotman, Y.: Combined Use of Genome-Wide Association Data and Correlation Networks Unravels Key Regulators of Primary Metabolism in Arabidopsis thaliana. PLoS Genetics 12 (10), e1006363 (2016)

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39.

Journal Article

Bozek, K.; Wei, Y.; Yan, Z.; Liu, X.; Xiong, J.; Sugimoto, M.; Tomita, M.; Paeaebo, S.; Sherwood, C. C.; Hof, P. R. et al.; Ely, J. J.; Li, Y.; Steinhauser, D.; Willmitzer, L.; Giavalisco, P.; Khaitovich, P.: Organization and Evolution of Brain Lipidome Revealed by Large-Scale Analysis of Human, Chimpanzee, Macaque, and Mouse Tissues. Neuron 85 (4), pp. 695 - 702 (2015)

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40.

Journal Article

Bromke, M. A.; Hochmuth, A.; Tohge, T.; Fernie, A. R.; Giavalisco, P.; Burgos, A.; Willmitzer, L.; Brotman, Y.: Liquid chromatography high-resolution mass spectrometry for fatty acid profiling. The Plant Journal 81 (3), pp. 529 - 536 (2015)

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41.

Journal Article

Bromke, M. A.; Sabir, J. S.; Alfassi, F. A.; Hajarah, N. H.; Kabli, S. A.; Al-Malki, A. L.; Ashworth, M. P.; Meret, M.; Jansen, R. K.; Willmitzer, L.: Metabolomic Profiling of 13 Diatom Cultures and Their Adaptation to Nitrate-Limited Growth Conditions. PLoS One 10 (10), e0138965 (2015)

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42.

Journal Article

Pant, B. D.; Burgos, A.; Pant, P.; Cuadros-Inostroza, A. C.; Willmitzer, L.; Scheible, W.-R.: The transcription factor PHR1 regulates lipid remodeling and triacylglycerol accumulation in Arabidopsis thaliana during phosphorus starvation. Journal of Experimental Botany 66 (7), pp. 1907 - 1918 (2015)

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43.

Journal Article

Sade, D.; Shriki, O.; Cuadros-Inostroza, A. C.; Tohge, T.; Semel, Y.; Haviv, Y.; Willmitzer, L.; Fernie, A. R.; Czosnek, H.; Brotman, Y.: Comparative metabolomics and transcriptomics of plant response to Tomato yellow leaf curl virus infection in resistant and susceptible tomato cultivars. Metabolomics 11 (1), pp. 81 - 97 (2015)

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44.

Journal Article

Szymanski, J.; Brotman, Y.; Willmitzer, L.; Cuadros-Inostroza, A. C.: Linking Gene Expression and Membrane Lipid Composition of Arabidopsis. The Plant Cell 26 (3), pp. 915 - 928 (2014)

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45.

Journal Article

Schulz, P.; Jansseune, K.; Degenkolbe, T.; Meret, M.; Claeys, H.; Skirycz, A.; Teige, M.; Willmitzer, L.; Hannah, M. A.: Poly(ADP-Ribose)Polymerase Activity Controls Plant Growth by Promoting Leaf Cell Number. PLoS One 9 (2), e90322 (2014)

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46.

Journal Article

Feher, K.; Lisec, J.; Römisch-Margl, L.; Selbig, J.; Gierl, A.; Piepho, H.-P.; Nikoloski, Z.; Willmitzer, L.: Deducing Hybrid Performance from Parental Metabolic Profiles of Young Primary Roots of Maize by Using a Multivariate Diallel Approach. PLoS ONE 9 (1), e85435 (2014)

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47.

Journal Article

Bozek, K.; Wei, Y.; Yan, Z.; Liu, X.; Xiong, J.; Sugimoto, M.; Tomita, M.; Paeaebo, S.; Pieszek, R.; Sherwood, C. C. et al.; Hof, P. R.; Ely, J. J.; Steinhauser, D.; Willmitzer, L.; Bangsbo, J.; Hansson, O.; Call, J.; Giavalisco, P.; Khaitovich, P.: Exceptional Evolutionary Divergence of Human Muscle and Brain Metabolomes Parallels Human Cognitive and Physical Uniqueness. PLoS Biology 12 (5), e1001871 (2014)

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48.

Journal Article

Meret, M.; Kopetzki, D.; Degenkolbe, T.; Kleessen, S.; Nikoloski, Z.; Tellstroem, V.; Barsch, A.; Kopka, J.; Antonietti, M.; Willmitzer, L.: From systems biology to systems chemistry: metabolomic procedures enable insight into complex chemical reaction networks in water. RSC Advances 4 (32), pp. 16777 - 16781 (2014)

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49.

Journal Article

Mettler, T.; Mühlhaus, T.; Hemme, D.; Schöttler, M. A.; Rupprecht, J.; Idoine, A.; Veyel, D.; Pal, S. K.; Yaneva-Roder, L.; Winck, F. V. et al.; Sommer, F.; Vosloh, D.; Seiwert, B.; Erban, A.; Burgos, A.; Arvidsson, S.; Schönfelder, S.; Arnold, A.; Günther, M.; Krause, U.; Lohse, M.; Kopka, J.; Nikoloski, Z.; Mueller-Roeber, B.; Willmitzer, L.; Bock, R.; Schroda, M.; Stitt, M.: Systems Analysis of the Response of Photosynthesis, Metabolism, and Growth to an Increase in Irradiance in the Photosynthetic Model Organism Chlamydomonas reinhardtii. The Plant Cell 26 (6), pp. 2310 - 2350 (2014)

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50.

Journal Article

Ramadan, A.; Sabir, J. S. M.; Alakilli, S. Y. M.; Shokry, A. M.; Gadalla, N. O.; Edris, S.; Al-Kordy, M. A.; Al-Zahrani, H. S.; El-Domyati, F. M.; Bahieldin, A. et al.; Baker, N. R.; Willmitzer, L.; Irgang, S.: Metabolomic Response of Calotropis procera Growing in the Desert to Changes in Water Availability. PLoS One 9 (2), e87895 (2014)

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