Max Planck Institute of Molecular Plant Physiology

Publications of Lothar Willmitzer

Journal Article (351)

1.

Journal Article

Schlossarek, D.; Luzarowski, M.; Sokolowska, E.; Gorka, M.; Willmitzer, L.; Skirycz, A.: PROMISed: A novel web-based tool to facilitate analysis and visualization of the molecular interaction networks from co-fractionation mass spectrometry (CF-MS) experiments. Computational and Structural Biotechnology Journal 19, pp. 5117 - 5125 (2021)

MPG.PuRe

2.

Journal Article

Luzarowski, M.; Vicente, R.; Kiselev, A.; Wagner, M.; Schlossarek, D.; Erban, A.; de Souza, L. P.; Childs, D.; Wojciechowska, I.; Luzarowska, U. et al.; Gorka, M.; Sokolowska, E.; Kosmacz, M.; Moreno, J.C.; Brzezinska, A.; Vegesna, B.; Kopka, J.; Fernie, A. R.; Willmitzer, L.; Ewald, J. C.; Skirycz, A.: Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity. Communications Biology 4 (1), 181 (2021)

MPG.PuRe

3.

Journal Article

Martín-Pizarro, C.; Vallarino, J. G.; Osorio, S.; Meco, V.; Urrutia, M.; Pillet, J.; Casañal, A.; Merchante, C.; Amaya, I.; Willmitzer, L. et al.; Fernie, A. R.; Giovannoni, J. J.; Botella, M. A.; Valpuesta, V.; Posé, D.: The NAC transcription factor FaRIF controls fruit ripening in strawberry. The Plant Cell 33 (5), pp. 1574 - 1593 (2021)

MPG.PuRe

4.

Journal Article

Cuadros-Inostroza, Á.; Verdugo-Alegría, C.; Willmitzer, L.; Moreno-Simunovic, Y.; Vallarino, J. G.: Non-Targeted Metabolite Profiles and Sensory Properties Elucidate Commonalities and Differences of Wines Made with the Same Variety but Different Cultivar Clones. Metabolites 10 (6), E220 (2020)

MPG.PuRe

5.

Journal Article

Pott, D. M.; Vallarino, J. G.; Cruz-Rus, E.; Willmitzer, L.; Sanchez-Sevilla, J. F.; Amaya, I.; Osorio, S.: Genetic analysis of phenylpropanoids and antioxidant capacity in strawberry fruit reveals mQTL hotspots and candidate genes. Scientific Reports 10 (1), 20197 (2020)

MPG.PuRe

6.

Journal Article

Pott, D. M.; de Abreu e Lima, F.; Soria, C.; Willmitzer, L.; Fernie, A. R.; Nikoloski, Z.; Osorio, S.; Vallarino, J. G.: Metabolic reconfiguration of strawberry physiology in response to postharvest practices. Food Chemistry 321, 126747 (2020)

MPG.PuRe

7.

Journal Article

Vallarino, J.G.; Merchante, C.; Sánchez-Sevilla, J.F.; de Luis Balaguer, M.A.; Pott, D.M.; Ariza, M.T.; Casañal, A.; Posé, D.; Vioque, A.; Amaya, I. et al.; Willmitzer, L.; Solano, R.; Sozzani, R.; Fernie, A. R.; Botella, M.A.; Giovannoni, J.J.; Valpuesta, V.; Osorio, S.: Characterizing the involvement of FaMADS9 in the regulation of strawberry fruit receptacle development. Plant Biotechnology Journal 18 (4), pp. 929 - 943 (2020)

MPG.PuRe

8.

Journal Article

Yu, Q.; He, Z.; Zubkov, D.; Huang, S.; Kurochkin, I.; Yang, X.; Halene, T.; Willmitzer, L.; Giavalisco, P.; Akbarian, S. et al.; Khaitovich, P.: Lipidome alterations in human prefrontal cortex during development, aging, and cognitive disorders. Molecular Psychiatry 25 (11), pp. 2952 - 2969 (2020)

MPG.PuRe

9.

Journal Article

Al-Aama, J.; Al Mahdi, H. B.; Salama, M. A.; Bakur, K.; Alhozali, A.; Mosli, H.; Bahijri, S. M.; Bahieldin, A.; Elango, R.; Willmitzer, L. et al.; Edris, S.: Rapid detection of type II diabetes mellitus in Saudi patients via simultaneous screening of multiple SNPs. Biotechnology & Biotechnology Equipment 33 (1), pp. 1319 - 1326 (2019)

MPG.PuRe

10.

Journal Article

Al-Aama, J.Y.; Mahdi, H.B.A.; Salama, M.A.; Bakur, K.H.; Alhozali, A.; Mosli, H.H.; Bahijri, S.M.; Bahieldin, A.; Willmitzer, L.; Edris, S.: Detection of secondary metabolites as biomarkers for the early diagnosis and prevention of type 2 diabetes. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 12, pp. 2675 - 2684 (2019)

MPG.PuRe

11.

Journal Article

Bozek, K.; Khrameeva, E. E.; Reznick, J.; Omerbašić, D.; Bennett, N. C.; Lewin, G. R.; Azpurua, J.; Gorbunova, V.; Seluanov, A.; Regnard, P. et al.; Wanert, F.; Marchal, J.; Pifferi, F.; Aujard, F.; Liu, Z.; Shi, P.; Pääbo, S.; Schröder, F.; Willmitzer, L.; Giavalisco, P.; Khaitovich, P.: Publisher Correction: Lipidome determinants of maximal lifespan in mammals. Scientific Reports 9 (1), 6972 (2019)

MPG.PuRe

12.

Journal Article

Goehring, I.; Sauter, N. S.; Catchpole, G.; Assmann, A.; Shu, L.; Zien, K. S.; Moehlig, M.; Pfeiffer, A. F. H.; Oberholzer, J.; Willmitzer, L. et al.; Spranger, J.; Maedler, K.: Correction to: Identification of an intracellular metabolic signature impairing beta cell function in the rat beta cell line INS-1E and human islets. Diabetologia 62 (3), pp. 553 - 554 (2019)

MPG.PuRe

13.

Journal Article

Goehring, I.; Sauter, N. S.; Catchpole, G.; Assmann, A.; Shu, L.; Zien, K. S.; Moehlig, M.; Pfeiffer, A. F. H.; Oberholzer, J.; Willmitzer, L. et al.; Spranger, J.; Maedler, K.: Identification of an intracellular metabolic signature impairing beta cell function in the rat beta cell line INS-1E and human islets (vol 54, pg 2584, 2011). Diabetologia 62 (3), pp. 553 - 554 (2019)

MPG.PuRe

14.

Journal Article

Kurochkin, I.; Khrameeva, E.; Tkachev, A.; Stepanova, V.; Vanyushkina, A.; Stekolshchikova, E.; Li, Q.; Zubkov, D.; Shichkova, P.; Halene, T. et al.; Willmitzer, L.; Giavalisco, P.; Akbarian, S.; Khaitovich, P.: Metabolome signature of autism in the human prefrontal cortex. Communications Biology 2 (1), 234 (2019)

MPG.PuRe

15.

Journal Article

Zhang, Q.; Wu, S.; Li, Y.; Liu, M.; Ni, K.; Yi, X.; Shi, Y.; Ma, L.; Willmitzer, L.; Ruan, J.: Characterization of three different classes of non-fermented teas using untargeted metabolomics. Food Research International 121, pp. 697 - 704 (2019)

MPG.PuRe

16.

Journal Article

de Abreu e Lima, F.; Li, K.; Wen, W.; Yan, J.; Nikoloski, Z.; Willmitzer, L.; Brotman, Y.: Unraveling lipid metabolism in maize with time-resolved multi-omics data. The Plant Journal 93 (6), pp. 1102 - 1115 (2018)

MPG.PuRe

17.

Journal Article

de Abreu e Lima, F.; Willmitzer, L.; Nikoloski, Z.: Classification-driven framework to predict maize hybrid field performance from metabolic profiles of young parental roots. PLoS One 13 (4), e0196038 (2018)

MPG.PuRe

18.

Journal Article

Vallarino, J. G.; de Abreu e Lima, F.; Soria, C.; Tong, H.; Pott, D. M.; Willmitzer, L.; Fernie, A. R.; Nikoloski, Z.; Osorio, S.: Genetic diversity of strawberry germplasm using metabolomic biomarkers. Scientific Reports 8 (1), 14386 (2018)

MPG.PuRe

19.

Journal Article

Veyel, D.; Sokolowska, E.; Moreno, J.C.; Kierszniowska, S.; Cichon, J.; Wojciechowska, I.; Luzarowski, M.; Kosmacz, M.; Szlachetko, J.; Gorka, M. et al.; Meret, M.; Graf, A.; Meyer, E. H.; Willmitzer, L.; Skirycz, A.: PROMIS, global analysis of PROtein-metabolite interactions using size separation in Arabidopsis thaliana. The Journal of Biological Chemistry 293 (32), pp. 12440 - 12453 (2018)

MPG.PuRe

20.

Journal Article

Wen, W.; Jin, M.; Li, K.; Liu, H.; Xiao, Y.; Zhao, M.; Alseekh, S.; Li, W.; de Abreu e Lima, F.; Brotman, Y. et al.; Willmitzer, L.; Fernie, A. R.; Yan, J.: An integrated multi-layered analysis of the metabolic networks of different tissues uncovers key genetic components of primary metabolism in maize. The Plant Journal 93 (6), pp. 1116 - 1128 (2018)

MPG.PuRe

21.

Journal Article

Wu, S.; Tohge, T.; Cuadros-Inostroza, A. C.; Tong, H.; Tenenboim, H.; Kooke, R.; Méret, M.; Keurentjes, J. B.; Nikoloski, Z.; Fernie, A. R. et al.; Willmitzer, L.; Brotman, Y.: Mapping the Arabidopsis Metabolic Landscape by Untargeted Metabolomics at Different Environmental Conditions. Molecular Plant 11 (1), pp. 118 - 134 (2018)

MPG.PuRe

22.

Journal Article

Bozek, K.; Khrameeva, E. E.; Reznick, J.; Omerbašić, D.; Bennett, N. C.; Lewin, G. R.; Azpurua, J.; Gorbunova, V.; Seluanov, A.; Regnard, P. et al.; Wanert, F.; Marchal, J.; Pifferi, F.; Aujard, F.; Liu, Z.; Shi, P.; Pääbo, S.; Schröder, F.; Willmitzer, L.; Giavalisco, P.; Khaitovich, P.: Lipidome determinants of maximal lifespan in mammals. Scientific Reports 7, 5 (2017)

MPG.PuRe

23.

Journal Article

Bucher, R.; Veyel, D.; Willmitzer, L.; Krattinger, S.; Keller, B.; Biglera, L.: Combined GC- and UHPLC-HR-MS Based Metabolomics to Analyze Durable Anti-fungal Resistance Processes in Cereals. Chimia 71 (4), pp. 156 - 159 (2017)

MPG.PuRe

24.

Journal Article

de Abreu e Lima, F.; Westhues, M.; Cuadros-Inostroza, Á.; Willmitzer, L.; Melchinger, A. E.; Nikoloski, Z.: Metabolic robustness in young roots underpins a predictive model of maize hybrid performance in the field. The Plant Journal 90 (2), pp. 319 - 329 (2017)

MPG.PuRe

25.

Journal Article

Jin, M.; Zhang, X.; Zhao, M.; Deng, M.; Du, Y.; Zhou, Y.; Wang, S.; Tohge, T.; Fernie, A. R.; Willmitzer, L. et al.; Brotman, Y.; Yan, J.; Weiwei, W.: Integrated genomics-based mapping reveals the genetics underlying maize flavonoid biosynthesis. BMC Plant Biology 17 (1), 17 (2017)

MPG.PuRe

26.

Journal Article

Li, Q.; Bozek, K.; Xu, C.; Guo, Y.; Sun, J.; Pääbo, S.; Sherwood, C. C.; Hof, P. R.; Ely, J. J.; Li, Y. et al.; Willmitzer, L.; Giavalisco, P.; Khaitovich, P.: Changes in lipidome composition during brain development in humans, chimpanzees, and macaque monkeys. Molecular Biology and Evolution 34 (5), pp. 1155 - 1166 (2017)

MPG.PuRe

27.

Journal Article

Luzarowski, M.; Kosmacz, M.; Sokolowska, E.; Jasinska, W.; Willmitzer, L.; Veyel, D.; Skirycz, A.: Affinity purification with metabolomic and proteomic analysis unravels diverse roles of nucleoside diphosphate kinases. Journal of Experimental Botany 68 (13), pp. 3487 - 3499 (2017)

MPG.PuRe

28.

Journal Article

Veyel, D.; Kierszniowska, S.; Kosmacz, M.; Sokolowska, E.; Michaelis, A.; Luzarowski, M.; Szlachetko, J.; Willmitzer, L.; Skirycz, A.: System-wide detection of protein-small molecule complexes suggests extensive metabolite regulation in plants. Scientific Reports 7, 42387 (2017)

MPG.PuRe

29.

Journal Article

Westhues, M.; Schrag, T. A.; Heuer, C.; Thaller, G.; Utz, H. F.; Schipprack, W.; Thiemann, A.; Seifert, F.; Ehret, A.; Schlereth, A. et al.; Stitt, M.; Nikoloski, Z.; Willmitzer, L.; Schoen, C. C.; Scholten, S.; Melchinger, A. E.: Omics-based hybrid prediction in maize. Theoretical and Applied Genetics 130 (9), pp. 1927 - 1939 (2017)

MPG.PuRe

30.

Journal Article

Wen, W.; Brotman, Y.; Willmitzer, L.; Yan, J.; Fernie, A. R.: Broadening Our Portfolio in the Genetic Improvement of Maize Chemical Composition. Trends in Genetics 32 (8), pp. 459 - 469 (2016)

MPG.PuRe

31.

Journal Article

Cuadros-Inostroza, A. C.; Ruiz-Lara, S.; Gonzalez, E.; Eckardt, A.; Willmitzer, L.; Pena-Cortes, H.: GC-MS metabolic profiling of Cabernet Sauvignon and Merlot cultivars during grapevine berry development and network analysis reveals a stage-and cultivar-dependent connectivity of primary metabolites. Metabolomics 12 (2), 39 (2016)

MPG.PuRe

32.

Journal Article

Machado, M.; Bromke, M. A.; Domingues Júnior, A.P.; Marçal Vieira Vaz, M.G.; Rosa, R.M.; Vinson, C.C.; Sabir, J.S.; Rocha, D.I.; Martins, M.A.; Araújo, W.L. et al.; Willmitzer, L.; Szymanski, J.; Nunes-Nesi, A.: Comprehensive metabolic reprograming in freshwater Nitzschia palea strains undergoing nitrogen starvation is likely associated with its ecological origin. Algal Research 18, pp. 116 - 126 (2016)

MPG.PuRe

33.

Journal Article

Riewe, D.; Jeon, H.-J.; Lisec, J.; Heuermann, M. C.; Schmeichel, J.; Seyfarth, M.; Meyer, R. C.; Willmitzer, L.; Altmann, T.: A naturally occurring promoter polymorphism of the Arabidopsis FUM2 gene causes expression variation, and is associated with metabolic and growth traits. The Plant Journal 88, pp. 826 - 838 (2016)

MPG.PuRe

34.

Journal Article

Rudovich, N. N.; Pivovarova, O.; Mazuch, J.; Wendt, S.; Tuvia, N.; Kruse, M.; Nikiforova, V.; Murahovschi, V.; Erban, A.; Mosig, A. et al.; Sticht, C.; Goegebakan, O.; Willmitzer, L.; Kramer, A.; Pfeiffer, A. F.: Insulin directly regulates clock gene expression in the insulin-dependent tissues in vivo and in vitro. Diabetologia 59, p. S324 - S324 (2016)

MPG.PuRe

35.

Journal Article

Scossa, F.; Brotman, Y.; de Abreu e Lima, F.; Willmitzer, L.; Nikoloski, Z.; Tohge, T.; Fernie, A. R.: Genomics-based strategies for the use of natural variation in the improvement of crop metabolism. Plant Science 242, pp. 47 - 64 (2016)

MPG.PuRe

36.

Journal Article

Skirycz, A.; Kierszniowska, S.; Meret, M.; Willmitzer, L.; Tzotzos, G.: Medicinal Bioprospecting of the Amazon Rainforest: A Modern Eldorado ? Trends in Biotechnology 34 (10), pp. 781 - 790 (2016)

MPG.PuRe

37.

Journal Article

Tenenboim, H.; Burgos, A.; Willmitzer, L.; Brotman, Y.: Using lipidomics for expanding the knowledge on lipid metabolism in plants. Biochimie 130, pp. 91 - 96 (2016)

MPG.PuRe

38.

Journal Article

Wu, S.; Alseekh, S.; Cuadros-Inostroza, A. C.; Fusari, C. M.; Mutwil, M.; Kooke, R.; Keurentjes, J. B.; Fernie, A. R.; Willmitzer, L.; Brotman, Y.: Combined Use of Genome-Wide Association Data and Correlation Networks Unravels Key Regulators of Primary Metabolism in Arabidopsis thaliana. PLoS Genetics 12 (10), e1006363 (2016)

MPG.PuRe

39.

Journal Article

Bozek, K.; Wei, Y.; Yan, Z.; Liu, X.; Xiong, J.; Sugimoto, M.; Tomita, M.; Paeaebo, S.; Sherwood, C. C.; Hof, P. R. et al.; Ely, J. J.; Li, Y.; Steinhauser, D.; Willmitzer, L.; Giavalisco, P.; Khaitovich, P.: Organization and Evolution of Brain Lipidome Revealed by Large-Scale Analysis of Human, Chimpanzee, Macaque, and Mouse Tissues. Neuron 85 (4), pp. 695 - 702 (2015)

MPG.PuRe

40.

Journal Article

Bromke, M. A.; Hochmuth, A.; Tohge, T.; Fernie, A. R.; Giavalisco, P.; Burgos, A.; Willmitzer, L.; Brotman, Y.: Liquid chromatography high-resolution mass spectrometry for fatty acid profiling. The Plant Journal 81 (3), pp. 529 - 536 (2015)

MPG.PuRe

41.

Journal Article

Bromke, M. A.; Sabir, J. S.; Alfassi, F. A.; Hajarah, N. H.; Kabli, S. A.; Al-Malki, A. L.; Ashworth, M. P.; Meret, M.; Jansen, R. K.; Willmitzer, L.: Metabolomic Profiling of 13 Diatom Cultures and Their Adaptation to Nitrate-Limited Growth Conditions. PLoS One 10 (10), e0138965 (2015)

MPG.PuRe

42.

Journal Article

Pant, B. D.; Burgos, A.; Pant, P.; Cuadros-Inostroza, A. C.; Willmitzer, L.; Scheible, W.-R.: The transcription factor PHR1 regulates lipid remodeling and triacylglycerol accumulation in Arabidopsis thaliana during phosphorus starvation. Journal of Experimental Botany 66 (7), pp. 1907 - 1918 (2015)

MPG.PuRe

43.

Journal Article

Sade, D.; Shriki, O.; Cuadros-Inostroza, A. C.; Tohge, T.; Semel, Y.; Haviv, Y.; Willmitzer, L.; Fernie, A. R.; Czosnek, H.; Brotman, Y.: Comparative metabolomics and transcriptomics of plant response to Tomato yellow leaf curl virus infection in resistant and susceptible tomato cultivars. Metabolomics 11 (1), pp. 81 - 97 (2015)

MPG.PuRe

44.

Journal Article

Szymanski, J.; Brotman, Y.; Willmitzer, L.; Cuadros-Inostroza, A. C.: Linking Gene Expression and Membrane Lipid Composition of Arabidopsis. The Plant Cell 26 (3), pp. 915 - 928 (2014)

MPG.PuRe

45.

Journal Article

Schulz, P.; Jansseune, K.; Degenkolbe, T.; Meret, M.; Claeys, H.; Skirycz, A.; Teige, M.; Willmitzer, L.; Hannah, M. A.: Poly(ADP-Ribose)Polymerase Activity Controls Plant Growth by Promoting Leaf Cell Number. PLoS One 9 (2), e90322 (2014)

MPG.PuRe

46.

Journal Article

Feher, K.; Lisec, J.; Römisch-Margl, L.; Selbig, J.; Gierl, A.; Piepho, H.-P.; Nikoloski, Z.; Willmitzer, L.: Deducing Hybrid Performance from Parental Metabolic Profiles of Young Primary Roots of Maize by Using a Multivariate Diallel Approach. PLoS ONE 9 (1), e85435 (2014)

MPG.PuRe

47.

Journal Article

Bozek, K.; Wei, Y.; Yan, Z.; Liu, X.; Xiong, J.; Sugimoto, M.; Tomita, M.; Paeaebo, S.; Pieszek, R.; Sherwood, C. C. et al.; Hof, P. R.; Ely, J. J.; Steinhauser, D.; Willmitzer, L.; Bangsbo, J.; Hansson, O.; Call, J.; Giavalisco, P.; Khaitovich, P.: Exceptional Evolutionary Divergence of Human Muscle and Brain Metabolomes Parallels Human Cognitive and Physical Uniqueness. PLoS Biology 12 (5), e1001871 (2014)

MPG.PuRe

48.

Journal Article

Meret, M.; Kopetzki, D.; Degenkolbe, T.; Kleessen, S.; Nikoloski, Z.; Tellstroem, V.; Barsch, A.; Kopka, J.; Antonietti, M.; Willmitzer, L.: From systems biology to systems chemistry: metabolomic procedures enable insight into complex chemical reaction networks in water. RSC Advances 4 (32), pp. 16777 - 16781 (2014)

MPG.PuRe

49.

Journal Article

Mettler, T.; Mühlhaus, T.; Hemme, D.; Schöttler, M. A.; Rupprecht, J.; Idoine, A.; Veyel, D.; Pal, S. K.; Yaneva-Roder, L.; Winck, F. V. et al.; Sommer, F.; Vosloh, D.; Seiwert, B.; Erban, A.; Burgos, A.; Arvidsson, S.; Schönfelder, S.; Arnold, A.; Günther, M.; Krause, U.; Lohse, M.; Kopka, J.; Nikoloski, Z.; Mueller-Roeber, B.; Willmitzer, L.; Bock, R.; Schroda, M.; Stitt, M.: Systems Analysis of the Response of Photosynthesis, Metabolism, and Growth to an Increase in Irradiance in the Photosynthetic Model Organism Chlamydomonas reinhardtii. The Plant Cell 26 (6), pp. 2310 - 2350 (2014)

MPG.PuRe

50.

Journal Article

Ramadan, A.; Sabir, J. S. M.; Alakilli, S. Y. M.; Shokry, A. M.; Gadalla, N. O.; Edris, S.; Al-Kordy, M. A.; Al-Zahrani, H. S.; El-Domyati, F. M.; Bahieldin, A. et al.; Baker, N. R.; Willmitzer, L.; Irgang, S.: Metabolomic Response of Calotropis procera Growing in the Desert to Changes in Water Availability. PLoS One 9 (2), e87895 (2014)

MPG.PuRe