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Das Max-Planck-Institut für Molekulare Pflanzenphysiologie hat regelmäßig herausragende Forscher zu Gast, die Vorträge über ihre aktuellen Projekte halten und so den Austausch unter den Wissenschaftlern fördern.

Eine Übersicht über die kommenden Veranstaltungen finden Sie hier. Seminare finden für gewöhnlich Mittwochs in der Zeit von 14:00 Uhr bis 15:30 Uhr im Seminarraum im Zentralgebäude (1.052 und 1.053) statt, Abweichungen in Zeit und Ort sind jedoch möglich.

Marja Timmermans - Small RNAs as mobile, morphogen-like signals in development

Abstract: Small RNAs as mobile, morphogen-like signals in development Damianos Skopelitis1, Anna Benkovics1, Aman Husbands1 and Marja Timmermans1,2 1) Cold Spring Harbor Laboratory, 1 Bungtown Rd, Cold Spring Harbor, NY 11724, USA 2) Center for Plant Molecular Biology, University of Tuebingen, Auf der Morgenstelle 32, 72076 Tuebingen, Germany Adaxial-abaxial (top-bottom) polarity drives the flattened outgrowth and patterning of leaves, and represents an important innovation in the evolution of land plants. Patterning of this axis is driven by an intricate gene regulatory network. Integral to this network are two sets of conserved transcription factors that promote either adaxial or abaxial fate, and are expressed in complementary domains on the top or bottom side of the leaf, respectively. The positional information needed to delineate these domains is provided in part by the small RNAs miR166 and tasiR-ARF. We have shown that these small RNAs move outside their defined domain of biogenesis and form opposing gradients across the leaf that polarize expression of key adaxial- and abaxial-promoting transcription factors, HD-ZIPIII and ARF3/4, respectively. Our observations, which will be presented, indicate that mobile small RNAs have the inherent capacity to generate sharp gene expression boundaries, and function as morphogen-like signals in development. Their patterning properties present small RNAs and their targets as highly portable regulatory modules through which to create pattern, and provides a compelling basis for the extensive conservation and repeated co-option of developmentally important small RNA-target modules. [mehr]

Sandra Schmoeckel - The genome of Chenopodium quinoa provides insights into saponin biosynthesis

Chenopodium quinoa (quinoa) is a highly nutritious grain crop with high abiotic stress tolerance that has been identified as an important crop to improve world food security; unfortunately, few resources are available to facilitate its genetic improvement. Here we report the assembly of a high-quality, chromosome-scale reference genome sequence for quinoa, which was produced using single-molecule real-time sequencing in combination with optical, chromosome contact, and genetic maps. We also report reduced-coverage genome sequences for 22 other accessions of the allotetraploid goosefoot complex and two diploids from among quinoa’s ancestral gene pools. The genome sequence facilitated the identification of the transcription factor likely to control the production of anti-nutritional triterpenoid saponins found in quinoa seeds, including a mutation that appears to cause alternative splicing and the inclusion of a premature stop codon, thereby inactivating the protein and leading to the absence of saponins in sweet quinoa accessions. These genomic resources are an important first step towards the genetic improvement of quinoa to help increase global food security in the face of climate change and a growing world population. [mehr]

March 2017

Keiko Sugimoto


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