The research focus of the group of Dr. Zoran Nikoloski is the development of methods for integration and analysis of 'omics' (time-resolved) data from high-throughput technologies in combination with the existing biological knowledge, structured in a form of ontologies and large-scale networks, in order to glean the design principles of biological processes.
Research in the group of Dr. Yariv Brotman focuses on the use of quantitative genetic approaches for the identification of genes that are involved in plant metabolism, and on further functional characterization of those genes by application of different molecular biology techniques and transgenic plant approaches. Special focus is given to genes that are taking part in lipid metabolism, but also genes that are taking parts in primary and secondary metabolism are investigated. The group is also integrating knowledge from classic lipid biochemistry with lipidomics in order to refine the knowledge on lipid biochemical pathways. [more]